EVALUATING EFFECTS OF LOW SERUM AMH ON OOCYTE MATURATION, EMBRYO DEVELOPMENT AND CLINICAL OUTCOME IN ASSISTED REPRODUCTIVE TECHNIQUES

Abstract

In the current scenarios, female infertility is on a rise. There are many causes of female infertility, however, Low Serum AMH leading to Poor Ovarian Reserve is one of the leading cause of infertility in females with age 35 or less. AMH also known as Anti Müllerian Hormone is one of the key hormone for ovarian reserve markers. A lower level of AMH, often indicates poor ovarian reserve. A correlation between the low level of serum AMH, oocyte quality and quantity, embryo quality and clinical outcome is unclear yet. This study aims in finding out the correlation between the low level of serum AMH, oocyte quality and quantity, embryo quality and clinical outcome. A short retrospective cohort study is done and the patients are categorized in two groups – Group I having patients with low AMH (less than 1.1 ng/ml) and Group II having patients with normal AMH (more than 1.1 ng/ml). The oocyte quality and quantity, embryo quality and clinical outcome of the patients are assessed and statistical analysis is performed. The results indicate that there is a correlation observed between low serum AHM levels, oocyte quality and quantity, embryo quality and clinical outcome. With lower levels of AMH, there is a decrease in the quantity of oocytes as well as there is a decrease in the quality of oocyte and embryo, leading to an overall decrease in the clinical outcome.